Spring 2014 – Isolated Orbital Mucormycosis in an Immunocompetent Adolescent

Isolated Orbital Mucormycosis in an Immunocompetent Adolescent.

Author: Jolie Krystle H. Guevara

Author Affiliations: University of the East Ramon Magsaysay Memorial Medical Center, Manila, Philippines

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Corresponding Author: Jolie Krystle H. Guevara; Jolieg800[at]gmail.com

Key Words: rhinocerebral; zygomycosis; pediatric; amphotericin B; corticosteroids; exenteration.

Abstract: Introduction and patient profile: Mucormycosis is a life-threatening disease that usually affects patients with diabetes and other immunocompromised states. However, recent literature has shown an emergence of this disease in immunocompetent individuals. Here we are presenting a rare case of a healthy 13-year-old adolescent diagnosed to have isolated orbital mucormycosis, previously treated with oral and intravenous corticosteroids. The patient presented with a chief complaint of left eye swelling of 3 weeks’ duration, which progressed to proptosis and a visual acuity of no light perception. Interventions and outcomes: Diagnosis of mucormycosis was done using histopathological techniques supported by radiologic imaging. Successful treatment of mucorymycosis was achieved via amphotericin B administration and orbital exenteration in this case. Discussion: The use of corticosteroids may weaken the immune system of healthy patients and can cause rapid progression of the disease. Early clinical diagnosis is important because this infection can rapidly be fatal.

Published on Date: May 31, 2014

Senior Editor: Jon Zande

Junior Editor: Romina Kim

DOI: Pending

Citation: Guevara JKH. Isolated Orbital Mucormycosis in an Immunocompetent Adolescent. Medical Student Research Journal. 2014;3(Spring):55-9.

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Jessica Wummel

Executive Editor
Jessica Wummel is a third year medical student at Michigan State University’s College of Human Medicine. She received her B.S. in Human Biology with a specialization in Bioethics, Humanities, and Society also from Michigan State University in 2011 from the Lyman Briggs College. She is interested in pursuing a career in Med/Peds and would eventually like to be involved in academic medicine later in her career.